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Mutation Information
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Mutation Site
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S219A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
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PubMed PMID
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19008175
|
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Disease
|
Liver cirrhosis
|
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Published Year
|
2008 |
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Journal
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European journal of medical research |
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Title
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Core promoter mutant HBV non-responding to adefovir after viral breakthrough on lamivudine: rapid virologic response to tenofovir plus lamivudine in a cirrhotic patient. |
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Author
|
Katsounas A,Jochum C,Canbay A,Schlaak J,Gerlich WH,Gerken G |
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Evidence
|
Because of unchanged VL sequence analysis was performed three months later, which showed the mutation (rtS219A) and the concomitant mutation (sS210R) and 2 mutations in core promoter region (A1762T), (G1764A).
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