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Mutation Information
|
Mutation Site
|
S262P |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
Literature Information
|
PubMed PMID
|
33712691
|
|
Published Year
|
2021 |
|
Journal
|
Communications biology |
|
Title
|
Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. |
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Author
|
Pandey KK,Bera S,Shi K,Rau MJ,Oleru AV,Fitzpatrick JAJ,Engelman AN,Aihara H,Grandgenett DP |
|
Evidence
|
Recombinant IN S262P was defective for CSC assembly while S262R formed octameric CSC intasomes, albeit at lower efficiency than wt IN (Supplementary Fig. 11).
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