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Mutation Information
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Mutation Site
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S366T |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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LMP1 |
Literature Information
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PubMed PMID
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32038504
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Published Year
|
2019 |
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Journal
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Frontiers in microbiology |
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Title
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Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α Activation. |
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Author
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Hatton O,Smith MM,Alexander M,Mandell M,Sherman C,Stesney MW,Hui ST,Dohrn G,Medrano J,Ringwalt K,Harris-Arnold A,Maloney EM,Krams SM,Martinez OM |
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Evidence
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All of the LMP1 tumor variants, but not B95.8 LMP1, contain the same point mutations in their C-terminal domains, each within a specific CTAR: a glycine to serine mutation at amino acid 212 in CTAR1 and a serine to threonine mutation at amino acid 366 in CTAR2.
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