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Mutation Information
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Mutation Site
|
S46A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
29792216
|
|
Published Year
|
2018 |
|
Journal
|
Retrovirology |
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Title
|
HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. |
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Author
|
Ivanov A,Lin X,Ammosova T,Ilatovskiy AV,Kumari N,Lassiter H,Afangbedji N,Niu X,Petukhov MG,Nekhai S |
|
Evidence
|
Pseudotyped HIV-1 with Tat S16E mutation replicated well, and HIV-1 Tat S46E:poorly, but no live viruses were obtained with Tat S16A or Tat S46A mutations.
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HIV Mutation Detail Information