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Mutation Information
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Mutation Site
|
S46D |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
29792216
|
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Published Year
|
2018 |
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Journal
|
Retrovirology |
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Title
|
HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. |
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Author
|
Ivanov A,Lin X,Ammosova T,Ilatovskiy AV,Kumari N,Lassiter H,Afangbedji N,Niu X,Petukhov MG,Nekhai S |
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Evidence
|
Binding to cyclin T1 showed decreased binding of all Ser-16 and Ser-46 Tat mutants with S16D and Tat S46D mutationts showing the strongest effect.
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HIV Mutation Detail Information