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Mutation Information
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Mutation Site
|
S62A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
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Combined Mutation
|
tat.T68A+tat.T64A+tat.S62A |
Literature Information
|
PubMed PMID
|
15737233
|
|
Published Year
|
2005 |
|
Journal
|
Virology journal |
|
Title
|
Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription. |
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Author
|
Endo-Munoz L,Warby T,Harrich D,McMillan NA |
|
Evidence
|
As can be seen from the figure, the phosphorylation of each protein by PKR varied and was the most efficient for wild-type Tat and the least efficient for the triple mutant, Tat S62A.
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HIV Mutation Detail Information