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Mutation Information
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Mutation Site
|
T109* |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
C |
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Genotype/Subtype
|
D |
Literature Information
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PubMed PMID
|
30089690
|
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Published Year
|
2018 |
|
Journal
|
Journal of virology |
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Title
|
Assembly Properties of Hepatitis B Virus Core Protein Mutants Correlate with Their Resistance to Assembly-Directed Antivirals. |
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Author
|
Ruan L,Hadden JA,Zlotnick A |
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Evidence
|
To test whether T109X mutants affect the physical chemistry of assembly and whether this may provide a basis for resistance, Cp149-T109X mutants were expressed in Escherichia coli and purified.
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HBV Mutation Detail Information