|
Mutation Information
|
Mutation Site
|
T118K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
11696228
|
|
Disease
|
HBV infection
|
|
Published Year
|
2001 |
|
Journal
|
Transfusion medicine (Oxford, England) |
|
Title
|
Characterization of a novel hepatitis B virus mutant: demonstration of mutation-induced hepatitis B virus surface antigen group specific "a" determinant conformation change and its application in diagnostic assays. |
|
Author
|
Kfoury Baz EM,Zheng J,Mazuruk K,Van Le A,Peterson DL |
|
Evidence
|
Interestingly, none of the mutations was found within the group-specific "a" determinant region (124-147) and, specifically, two of the five mutations, T118K and P120Q, were located only a few amino acids adjacent to the 124-147 region.
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HBV Mutation Detail Information