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Mutation Information
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Mutation Site
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T131N |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
|
Country
|
US |
Literature Information
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PubMed PMID
|
32512942
|
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Published Year
|
2020 |
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Journal
|
Cells |
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Title
|
N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis. |
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Author
|
Dobrica MO,Lazar C,Branza-Nichita N |
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Evidence
|
Moreover, they are often detected several years before HCC onset, raising the question of a direct involvement of N-linked glycans in disease progression. Recently, twenty additional N-glycosylation sites have been reported in HBsAg/anti-HBsAg antibodies-coexistent patients, of which the previously characterized T131N+M133T mutations (Table 1) were clearly the dominant pattern, being detected in more than 50% of cases.
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HBV Mutation Detail Information