|
Mutation Information
|
Mutation Site
|
T1753V |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
A |
|
Viral Reference
|
AY233274.1
|
|
Country
|
Black South African |
Literature Information
|
PubMed PMID
|
32504396
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2020 |
|
Journal
|
Archives of virology |
|
Title
|
Molecular characterization of hepatitis B virus isolated from Black South African cancer patients, with and without hepatocellular carcinoma. |
|
Author
|
Mak D,Kramvis A |
|
Evidence
|
Of the 19 isolates from HBeAg-positive sera, 12 had mutations in the BCP: one had T1753V (MK503763) and nine had A1762T/G1764A (MK491814, MK491826, MK491818, MK491799, MK503736, MK503756, MK503763, MK503741, MK491825); sample MK503747 had A1762T/G1764A, whereas MK491813 had a deletion at position 1764; one had TCTT at nt 1809-1812 (MK491816).
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HBV Mutation Detail Information