HBV Mutation Detail Information

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Mutation Information

Mutation Site	T1768A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	B3
Country	Indonesia

Literature Information

PubMed PMID	22095534
Disease	HBV associated liver disease
Published Year	2012
Journal	Journal of medical virology
Title	Mutations within enhancer II and BCP regions of hepatitis B virus in relation to advanced liver diseases in patients infected with subgenotype B3 in Indonesia.
Author	Heriyanto DS,Yano Y,Utsumi T,Anggorowati N,Rinonce HT,Lusida MI,Soetjipto,Triwikatmani C,Ratnasari N,Maduseno S,Purnama PB,Nurdjanah S,Hayashi Y
Evidence	The other point mutations within this region, T1753V and T1768A, leading to amino acid substitutions from isoleucine to threonine or asparagine and from phenylalanine to tyrosine, respectively, were also found more frequently in advanced liver diseases than those with chronic hepatitis B (P < 0.05; Table II).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation