|
Mutation Information
|
Mutation Site
|
T178A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24099556
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2013 |
|
Journal
|
BMC cancer |
|
Title
|
Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China. |
|
Author
|
Sun Z,Lu Z,Liu J,Wang G,Zhou W,Yang L,Liu C,Wang B,Ruan Q |
|
Evidence
|
Based on the HPV16 prototype, the most frequent variation in the E6 gene was T178A/G (48.7%), followed by mutations of G94A (12.2%) and T350G (9.9%).
|
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|