|
Mutation Information
|
Mutation Site
|
T184L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.T184L+rt.L180M |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30796932
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Antiviral research |
|
Title
|
Prevalence of the entecavir-resistance-inducing mutation rtA186T in a large cohort of Chinese hepatitis B virus patients. |
|
Author
|
Liu L,Liu Y,Chen R,Li X,Luo D,Zhao Y,Li Q,Huang B,Wang FS,Liu X,Xu D |
|
Evidence
|
At month 49, HBV DNA increased to 5.1 log10 IU/mL and the dominant mutation pattern was changed to rtL180M+T184L+M204V
|
|
|