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Mutation Information
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Mutation Site
|
T184R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
18435459
|
|
Disease
|
HBV infection
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Comprehensive evaluation of hepatitis B virus reverse transcriptase substitutions associated with entecavir resistance. |
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Author
|
Baldick CJ,Tenney DJ,Mazzucco CE,Eggers BJ,Rose RE,Pokornowski KA,Yu CF,Colonno RJ |
|
Evidence
|
Although many replicated as well as the LVDr virus control, reduced replication was observed for charged residues rtT184R, K, H, and D, and to a lesser degree for E.
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