HIV Mutation Detail Information

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Mutation Information

Mutation Site	T192M
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp120
Amino acid_Mutation	C6795T

Literature Information

PubMed PMID	28100611
Published Year	2017
Journal	Journal of virology
Title	The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block.
Author	Rihn SJ,Foster TL,Busnadiego I,Aziz MA,Hughes J,Neil SJD,Wilson SJ
Evidence	Perhaps more importantly, of the three total polymorphisms that were detected in the swarm propagated in the presence of IFN-gamma, only one was selected to uniformity (Fig. 9B and C). This single transition, C6795T, encodes a nonsynonymous substitution in variable region 2 (V2) of the envelope glycoprotein (Env), T192M.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation