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Mutation Information
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Mutation Site
|
T215F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
tenofovir (TDF);zidovudine (AZT);lamivudine (LAM) |
|
Country
|
Burkina Faso |
Literature Information
|
PubMed PMID
|
30079168
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Journal of public health in Africa |
|
Title
|
Human immunodeficiency virus type 1 drug resistance in a subset of mothers and their infants receiving antiretroviral treatment in Ouagadougou, Burkina Faso. |
|
Author
|
Soubeiga ST,Bazie BVJTE,Compaore TR,Ouattara AK,Zohoncon TM,Obiri-Yeboah D,Yonli AT,Zongo A,Traore L,Pietra V,Akpona S,Diagbouga S,Simpore J |
|
Evidence
|
As reported in other studies,10,21 M184V was the most frequent in this study and was associated with high-level resistance to 3TC, FTC, and ABC. Others mutations detected such as T215F/Y, D67N/E, K70R, and K219Q are associated with intermediate resistance to TDF, AZT, and 3TC.
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HIV Mutation Detail Information