|
Mutation Information
|
Mutation Site
|
T215F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
Literature Information
|
PubMed PMID
|
31025011
|
|
Published Year
|
2019 |
|
Journal
|
Heliyon |
|
Title
|
Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance. |
|
Author
|
Mohammadzadeh N,Love RP,Gibson R,Arts EJ,Poon AFY,Chelico L |
|
Evidence
|
Although the T215F/Y mutation that results in stronger AZT resistance was found in gRNA, the D67N mutation was 2.4-fold more frequent, consistent with A3F-induced mutagenesis (Figs. (Figs.2C2C and and4I).4I).
|
|
|