|
Mutation Information
|
Mutation Site
|
T215S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NRTIs |
|
Country
|
Canada |
Literature Information
|
PubMed PMID
|
19005274
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Transmission networks of drug resistance acquired in primary/early stage HIV infection. |
|
Author
|
Brenner BG,Roger M,Moisi DD,Oliveira M,Hardy I,Turgel R,Charest H,Routy JP,Wainberg MA,Montreal PHI Cohort and HIV Prevention Study Groups. |
|
Evidence
|
As shown, viral variants harbouring mutations to NRTIs, including revertants at codon 215 (T215C/D/I/N/S), thymidine analogue mutations, and M184V, as well as to PIs were less frequent in clustered transmissions.
|
|
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HIV Mutation Detail Information