|
Mutation Information
|
Mutation Site
|
T26S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
33316353
|
|
Published Year
|
2021 |
|
Journal
|
Virus research |
|
Title
|
Conditional activation of an HIV-1 protease attenuated mutant by a leucine zipper dimerization motif. |
|
Author
|
Yu FH,Huang KJ,Wang CT |
|
Evidence
|
However, introducing T26S (a PR activity-attenuated mutation) into DWzPR strongly impaired Gag cleavage, except when the native C-terminal p6* tetrapeptide remained at the LZ/PR junction.
|
|
|
HIV Mutation Detail Information