|
Mutation Information
|
Mutation Site
|
T350G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
NC_001526
|
Literature Information
|
PubMed PMID
|
27654117
|
|
Disease
|
Squamous-cell carcinoma
|
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Published Year
|
2016 |
|
Journal
|
Cancer medicine |
|
Title
|
HPV16 variants distribution in invasive cancers of the cervix, vulva, vagina, penis, and anus. |
|
Author
|
Nicolás-Párraga S,Gandini C,Pimenoff VN,Alemany L,de Sanjosé S,Xavier Bosch F,Bravo IG,RIS HPV TT and HPV VVAP study groups. |
|
Evidence
|
Frequencies for alleles in the HPV16 E6 T350G polymorphism were similar across anogenital cancers from the same geographical origin. Interestingly, anogenital cancers from Central/South America displayed higher 350G allele frequencies also within HPV16_A1‐3 lineage compared with Europe.
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