|
Mutation Information
|
Mutation Site
|
T350G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Nucleotide_Mutation
|
L83V |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Mexico |
Literature Information
|
PubMed PMID
|
32320400
|
|
Disease
|
HIV-HPV co-infection
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
High prevalence of human papillomavirus and European variants of HPV 16 infecting concomitantly to cervix and oral cavity in HIV positive women. |
|
Author
|
Pérez-Quintanilla M,Méndez-Martínez R,Vázquez-Vega S,Espinosa-Romero R,Sotelo-Regil R,Pérez-Montiel MD,Ramos-Alamillo U,Cabrera-López TJ,Barquet-Muñoz SA,Pérez-Plascencia C,García-Carrancá A,Cantú de León D |
|
Evidence
|
The 350T-G substitution (E-350G) in the E6 gene of HPV16 has been proposed as an additional risk factor for persistent infection and the cytologic progression of grade 2/3 CIN and squamous cell carcinoma (SCC).
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HPV Mutation Detail Information