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Mutation Information
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Mutation Site
|
T53C |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreS2 |
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Country
|
China |
Literature Information
|
PubMed PMID
|
24849936
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in Qidong, China. |
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Author
|
Qu LS,Liu JX,Liu TT,Shen XZ,Chen TY,Ni ZP,Lu CH |
|
Evidence
|
RESULTS: After adjustment for age, history of cigarette smoking and alcohol consumption, HBeAg positivity, pre-S deletions, pre-S2 start codon mutations, and T53C mutation were significantly associated with HCC, showing adjusted odds ratios (ORs) from 1.
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