|
Mutation Information
|
Mutation Site
|
T540C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
S |
|
Nucleotide_Mutation
|
Q129R |
Literature Information
|
PubMed PMID
|
9303514
|
|
Clinical information
|
Yes
|
|
Disease
|
Fulminant hepatitis B;
Acute hepatitis B
|
|
Published Year
|
1997 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis. |
|
Author
|
Hsu HY,Chang MH,Ni YH,Lin HH,Wang SM,Chen DS |
|
Evidence
|
patient 8 (C) had S mutant with T-to-C mutation at nucleotide position 540 , leading to amino acid change from glycine to arginine at residue 129
|
|
|