|
Mutation Information
|
Mutation Site
|
T7744C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
LCR |
|
Genotype/Subtype
|
HPV52 |
|
Country
|
Canada |
Literature Information
|
PubMed PMID
|
23015309
|
|
Disease
|
Cervical intraepithelial neoplasia
|
|
Published Year
|
2013 |
|
Journal
|
International journal of cancer |
|
Title
|
Human papillomavirus type 52 polymorphism and high-grade lesions of the uterine cervix. |
|
Author
|
Formentin A,Archambault J,Koushik A,Richardson H,Brassard P,Franco EL,Coutlée F |
|
Evidence
|
CIN2,3 risk was significantly associated with a deletion at nucleotide position 7695 in the LCR (OR 4.9, 95% CI 1.2-20.8), the T7744C variation in the LCR (OR 5.7, 95% CI 1.1-32.0), and the K93R variation in E6 (OR 6.9, 95% CI 1.3-36.8), after adjusting for age, detection of HPV16 or 18 and study site.
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