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Mutation Information
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Mutation Site
|
T8I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gag |
Literature Information
|
PubMed PMID
|
33863979
|
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Published Year
|
2021 |
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Journal
|
Communications biology |
|
Title
|
CryoET structures of immature HIV Gag reveal six-helix bundle. |
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Author
|
Mendonça L,Sun D,Ning J,Liu J,Kotecha A,Olek M,Frosio T,Fu X,Himes BA,Kleinpeter AB,Freed EO,Zhou J,Aiken C,Zhang P |
|
Evidence
|
A single amino acid mutation (T8I) in SP1 stabilizes the six-helix bundle, allowing to discern the entire CA-SP1 helix connecting to the NC domain.
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HIV Mutation Detail Information