HIV Mutation Detail Information

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Mutation Information

Mutation Site	V106M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Relevant Drug	NNRTIs
Country	South Africa

Literature Information

PubMed PMID	32772079
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of antimicrobial chemotherapy
Title	Impact of pretreatment low-abundance HIV-1 drug-resistant variants on virological failure among HIV-1/TB-co-infected individuals.
Author	Chimukangara B,Giandhari J,Lessells R,Yende-Zuma N,Sartorius B,Samuel R,Khanyile KS,Stray-Pedersen B,Moodley P,Metzner KJ,Padayatchi N,Naidoo K,De Oliveira T
Evidence	The NNRTI mutation V106AI became a majority V106M mutation at VF in two cases, whilst the NRTI mutation L74I became a majority L74V mutation in one case, and the NRTI mutation K65R became a majority DRM in one case (Table S3).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation