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Mutation Information
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Mutation Site
|
V118I |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
|
B |
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Relevant Drug
|
NRTIs |
Literature Information
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PubMed PMID
|
17500586
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Disease
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HIV infection/AIDS
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Published Year
|
2007 |
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Journal
|
PLoS computational biology |
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Title
|
HIV-1 subtype B protease and reverse transcriptase amino acid covariation. |
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Author
|
Rhee SY,Liu TF,Holmes SP,Shafer RW |
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Evidence
|
Positively associated mutation pairs consisted primarily of Type I or II thymidine analog mutations (TAMs;as defined in Methods);accessory NRTI mutations that occurred in combination with Type I or II TAMs (K43E, E44D, V118I, H208Y, D218E);and Q151M-associated mutations (V75I, F77L, F116Y).
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