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Mutation Information
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Mutation Site
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V131I |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BCP |
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Amino acid_Mutation
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G1764A |
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Genotype/Subtype
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B;C |
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Country
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China |
Literature Information
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PubMed PMID
|
26647737
|
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Disease
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Chronic hepatitis B
|
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Published Year
|
2015 |
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Journal
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Scientific reports |
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Title
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Deep sequencing of hepatitis B virus basal core promoter and precore mutants in HBeAg-positive chronic hepatitis B patients. |
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Author
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Yan L,Zhang H,Ma H,Liu D,Li W,Kang Y,Yang R,Wang J,He G,Xie X,Wang H,Wei L,Lu Z,Shao Q,Chen H |
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Evidence
|
As shown in Fig. 3, besides classical A1762T/G1764A and G1896A mutants affecting codons 130/131 of X gene (K130M/V131I) and codon 28 of PC gene (W28stop), another 12 SNPs (nt.1719, nt.1726, nt.1727, nt.1730, nt.1752, nt.1753, nt.1768, nt.1800, nt.1803, nt.1804, nt.1805 and nt.1825) also caused amino acid changes.
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HBV Mutation Detail Information