|
Mutation Information
|
Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
24790911
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2014 |
|
Journal
|
Annals of laboratory medicine |
|
Title
|
Analysis of reverse transcriptase gene mutations in the hepatitis B virus at a university hospital in Korea. |
|
Author
|
Lee AJ,Lee CH,Jeon CH |
|
Evidence
|
When the rtM204V and rtM204I mutation groups were compared, all 72 cases of rtM204V mutation had a simultaneous rtL180M mutation, while in 79 cases of rtM204I mutation, 43 cases (54.4%) had a simultaneous rtL180M mutation, 33 cases (41.8%) had the rtM204I mutation alone, and the remaining 3 cases (3.8%) showed a simultaneous rtV173L mutation
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