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Mutation Information
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Mutation Site
|
V173L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
|
A;B;C;D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China;Canada;Italy |
Literature Information
|
PubMed PMID
|
29713126
|
|
Published Year
|
2018 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
|
Author
|
Choi YM,Lee SY,Kim BJ |
|
Evidence
|
These authors also showed that 10 percent, 3 out of 29 patients prior to the initiation of antiretroviral therapy (ART), had drug resistance mutations rtV173L, rtL180M+rtM204V, and rtV214A. In South Africa, rtM204I has been mainly detected in treatment-naïve HBV/HIV co-infected individuals
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