HBV Mutation Detail Information

> V173M Search Result

Mutation Information

Mutation Site	V173M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A
Viral Reference	X02763
Country	Asia‐Pacific;Europe

Literature Information

PubMed PMID	32579776
Disease	Chronic hepatitis B
Published Year	2020
Journal	Journal of viral hepatitis
Title	Virology analysis of chronic hepatitis B virus-infected patients treated for 28 days with JNJ-56136379 monotherapy.
Author	Verbinnen T,Hodari M,Talloen W,Berke JM,Blue D,Yogaratnam J,Vandenbossche J,Shukla U,De Meyer S,Lenz O
Evidence	One placebo‐treated patient (HBeAg‐negative, GT‐D) carried the secondary NA‐resistance mutation V173V/M as baseline polymorphism. None of the 28 JNJ‐6379‐treated patients with paired baseline and post‐baseline HBV RT‐domain sequence information had an emerging NA‐resistance mutation.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation