|
Mutation Information
|
Mutation Site
|
V179E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
tenofovir (TDF);lamivudine (LAM);efavirenz (EFV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32878449
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Genetic Diversity, Complicated Recombination, and Deteriorating Drug Resistance Among HIV-1-Infected Individuals in Wuhan, China. |
|
Author
|
Zhang Y,Luo Y,Li Y,Zhang Y,Wu W,Peng H,Han L,Chen Y,Ruan L,Yang R |
|
Evidence
|
Among the 93 subjects of antiretroviral therapy (ART)-naive, transmitted drug resistance against non-nucleoside reverse transcriptase inhibitors (NNRTIs) was 23.9%, of which V179D/E was the most frequent mutation, accounting for 18.2%.
|
|
|