|
Mutation Information
|
Mutation Site
|
V191I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A;G |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
19301976
|
|
Disease
|
Chronic hepatitis B;
HBV-HIV coinfection
|
|
Published Year
|
2009 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Ultra-deep pyrosequencing of hepatitis B virus quasispecies from nucleoside and nucleotide reverse-transcriptase inhibitor (NRTI)-treated patients and NRTI-naive patients. |
|
Author
|
Margeridon-Thermet S,Shulman NS,Ahmed A,Shahriar R,Liu T,Wang C,Holmes SP,Babrzadeh F,Gharizadeh B,Hanczaruk B,Simen BB,Egholm M,Shafer RW |
|
Evidence
|
Three of the 13 residues with stop codons were always associated with RT amino acid mutations, of which 2 (rtA181T and rtV191I) have previously been reported.
|
|
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HBV Mutation Detail Information