HIV Mutation Detail Information

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Mutation Information

Mutation Site	V423A
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	31943114
Published Year	2020
Journal	Nucleic acids research
Title	Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase.
Author	Nguyen PDM,Zheng J,Gremminger TJ,Qiu L,Zhang D,Tuske S,Lange MJ,Griffin PR,Arnold E,Chen SJ,Zou X,Heng X,Burke DH
Evidence	The singly substituted p51 subunits were co-expressed with wild-type p66 and purified to yield eight enzymatically active mutant RTs (N418A, T419A, P420A, P421A, L422A, V423A, K424A and L425A) (Supplementary Figure S11).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation