|
Mutation Information
|
Mutation Site
|
V542I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
penciclovir (PCV);famciclovir (FCV) |
Literature Information
|
PubMed PMID
|
9862871
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
1999 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance. |
|
Author
|
Pichoud C,Seignères B,Wang Z,Trépo C,Zoulim F |
|
Evidence
|
The results showed the transient selection of a V542I mutant in the C domain of the viral polymerase.
|
|
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HBV Mutation Detail Information