|
Mutation Information
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Mutation Site
|
V82A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
PIs |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
33632139
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
BMC infectious diseases |
|
Title
|
Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa. |
|
Author
|
Obasa AE,Ambikan AT,Gupta S,Neogi U,Jacobs GB |
|
Evidence
|
The majority of the drug resistance mutations in the minor viral quasispecies were observed in the V82A mutation (n = 13) in protease and K65R (n = 5), K103N (n = 7) and M184V (n = 5) in reverse transcriptase.
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HIV Mutation Detail Information