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Mutation Information
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Mutation Site
|
V89A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Tax |
Literature Information
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PubMed PMID
|
11080799
|
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Published Year
|
2000 |
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Journal
|
AIDS research and human retroviruses |
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Title
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Kinase-inducible domain-like region of HTLV type 1 tax is important for NF-kappaB activation. |
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Author
|
Kuo YL,Tang Y,Harrod R,Cai P,Giam CZ |
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Evidence
|
Here we report that single (K88A, V89A, L90A) and double alanine substitutions (V89A-L90A) in the (88)KVL(90) motif attenuate the ability of Tax to activate NF-kappaB.
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HTLV1 Mutation Detail Information