HBV Mutation Detail Information

> W153Q Search Result

Mutation Information

Mutation Site	W153Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A

Literature Information

PubMed PMID	19889778
Published Year	2010
Journal	Journal of virology
Title	Differential impact of immune escape mutations G145R and P120T on the replication of lamivudine-resistant hepatitis B virus e antigen-positive and -negative strains.
Author	Amini-Bavil-Olyaee S,Vucur M,Luedde T,Trautwein C,Tacke F
Evidence	Because this mutation simultaneously results in a substitution in the polymerase protein (rtW153Q), it could possibly affect the already impaired replication of LAM-resistant viruses.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation