|
Mutation Information
|
Mutation Site
|
W172* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Rome |
Literature Information
|
PubMed PMID
|
19442845
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virological methods |
|
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
|
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
|
Evidence
|
In addition, in a patient with HBV DNA of 1260 IU/mL, treated with LAM for 2 years, the recently described mutation rtA181T (Warner and Locarnini, 2008) corresponding to a stop codon in HBsAg (sW172stop) was detected by the direct sequencing method.
|
|
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HBV Mutation Detail Information