HBV Mutation Detail Information

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Mutation Information

Mutation Site	W172L
Mutation Type	Amino acid level
Gene/Protein/Region Type	S

Literature Information

PubMed PMID	26201776
Published Year	2013
Journal	Hepatology international
Title	Hepatitis B virus genotype C encoding resistance mutations that emerge during adefovir dipivoxil therapy: in vitro replication phenotype.
Author	Li W,Warner N,Sozzi V,Yuen L,Colledge D,Li T,Zhuang H,Locarnini S,Revill PA
Evidence	A slight defect in HBsAg secretion was observed in HBV encoding both rtA181T/sW172L and rtA181T/sW172L + rtN236T; however, intracellular HBsAg levels were comparable with the other HBV variants tested (Fig. 4a).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation