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Mutation Information
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Mutation Site
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W172L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
S |
Literature Information
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PubMed PMID
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29609638
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Published Year
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2018 |
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Journal
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Virology journal |
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Title
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The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathway. |
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Author
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Wang ML,Wu DB,Tao YC,Chen LL,Liu CP,Chen EQ,Tang H |
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Evidence
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Though the ratio of cell clones were less than 20% in either L02-pcDNA3.1, L02-pcDNA3.1-HBs(wt), L02-pcDNA3.1-HBs(sW172L) or L02-pcDNA3.1-HBs(sW172*), the ratio of cell clones was more in L02-pcDNA3.1-HBs(sW172*) than other three groups (Fig. 1).
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HBV Mutation Detail Information