HBV Mutation Detail Information

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Mutation Information

Mutation Site	W196*
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Relevant Drug	lamivudine (LAM)
Country	Thailand

Literature Information

PubMed PMID	22860080
Disease	HBV-HIV coinfection
Published Year	2012
Journal	PloS one
Title	Long-term hepatitis B virus (HBV) response to lamivudine-containing highly active antiretroviral therapy in HIV-HBV co-infected patients in Thailand.
Author	Khamduang W,Gaudy-Graffin C,Ngo-Giang-Huong N,Jourdain G,Moreau A,Luekamlung N,Halue G,Buranawanitchakorn Y,Kunkongkapan S,Buranabanjasatean S,Lallemant M,Sirirungsi W,Goudeau A,Program for HIV Prevention and Treatment Study Group.
Evidence	This mutation led to the concomitant substitution of tryptophan to stop codon at position 196 (sW196stop) in the surface protein.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation