HBV Mutation Detail Information

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Mutation Information

Mutation Site	W196L
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Combined Mutation	s.W196L+rt.M204I

Literature Information

PubMed PMID	22082274
Disease	HBV associated liver disease
Published Year	2011
Journal	Biochemistry. Biokhimiia
Title	Antiviral resistance mutations potentiate HBV surface antigen-induced transcription of hfgl2 prothrombinase gene.
Author	Li W,Han M,Li Y,Chen D,Luo X,Ning Q
Evidence	To investigate whether the nucleotide (nucleoside)-induced resistant mutations of HBs potentiate transcription of hfgl2 prothrombinase gene, we generated two mutant HB expression constructs harboring rtM204V/sI195M or rtM204I/sW196L mutations.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation