|
Mutation Information
|
Mutation Site
|
W28* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreC |
|
Amino acid_Mutation
|
G1896A |
|
Genotype/Subtype
|
A;D;F |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
15932365
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Alimentary pharmacology & therapeutics |
|
Title
|
Changes in different regions of hepatitis B virus gene in hepatitis B 'e' antigen-negative patients with chronic hepatitis B: the effect of long-term lamivudine therapy. |
|
Author
|
Buti M,Jardi R,Rodriguez-Frias F,Valdes A,Schaper M,Esteban R,Guardia J |
|
Evidence
|
The predominant mutation substitutes G for A at nucleotide 1896 (G1896A), this creates a premature stop codon at codon 28.
|
|
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HBV Mutation Detail Information