|
Mutation Information
|
Mutation Site
|
W28* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreC |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T+prec.G1896A;prec.G1899A+bcp.G1764A+bcp.A1762T+prec.G1896A |
|
Amino acid_Mutation
|
G1896A |
|
Genotype/Subtype
|
D |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
16789012
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Journal of medical virology |
|
Title
|
Basal core promoter, precore region mutations of HBV and their association with e antigen, genotype, and severity of liver disease in patients with chronic hepatitis B in India. |
|
Author
|
Chauhan R,Kazim SN,Bhattacharjee J,Sakhuja P,Sarin SK |
|
Evidence
|
The Pc stop codon mutation, G1896A(W28Stop), was seen in 12 (33%) of 36 HBeAg-negative patients and only 1 (2%) e-antigen-positive patient (P < 0.01) (Table II).
|
|
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HBV Mutation Detail Information