|
Mutation Information
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Mutation Site
|
W427V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp120 |
Literature Information
|
PubMed PMID
|
33832362
|
|
Published Year
|
2021 |
|
Journal
|
SAR and QSAR in environmental research |
|
Title
|
E-pharmacophore based screening to identify potential HIV-1 gp120 and CD4 interaction blockers for wild and mutant types. |
|
Author
|
Chandra I,Prabhu SV,Nayak C,Singh SK |
|
Evidence
|
Most importantly, compound NCI-254200 displayed strong communication with key residues of wild type and drug resistance single mutant gp120 (M426L and W427V) even in the dynamic condition, evidenced from MD simulation.
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HIV Mutation Detail Information