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Mutation Information
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Mutation Site
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W54G |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vpr |
Literature Information
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PubMed PMID
|
18808682
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Published Year
|
2008 |
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Journal
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Retrovirology |
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Title
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Direct Vpr-Vpr interaction in cells monitored by two photon fluorescence correlation spectroscopy and fluorescence lifetime imaging. |
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Author
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Fritz JV,Didier P,Clamme JP,Schaub E,Muriaux D,Cabanne C,Morellet N,Bouaziz S,Darlix JL,Mély Y,de Rocquigny H |
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Evidence
|
Moreover, the W54G mutant was shown to be critical for the interaction with cellular UNG (Uracil DNA glycosilase) and its virion incorporation.
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