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Mutation Information
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Mutation Site
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Y116F |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
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Relevant Drug
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entecavir (ETV);lamivudine (LAM);tenofovir alafenamide (TAF);islatravir (ISL);zidovudine (AZT) |
Literature Information
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PubMed PMID
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32080249
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Published Year
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2020 |
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Journal
|
Scientific reports |
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Title
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Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. |
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Author
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Yasutake Y,Hattori SI,Tamura N,Matsuda K,Kohgo S,Maeda K,Mitsuya H |
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Evidence
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Therefore, we chose three corresponding mutations, M184V, F160M, and Q182G, in HIV-1 RT to investigate resistance to 3TC/ETV in HIV-1F115Y/Y116F/Q151M to 3TC and ETV.
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HIV Mutation Detail Information