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Mutation Information
|
Mutation Site
|
Y132A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
C |
Literature Information
|
PubMed PMID
|
19196007
|
|
Published Year
|
2009 |
|
Journal
|
Biochemistry |
|
Title
|
A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly. |
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Author
|
Bourne CR,Katen SP,Fulz MR,Packianathan C,Zlotnick A |
|
Evidence
|
Here we use Cp149, the assembly domain of the hepatitis B virus capsid protein, together with an assembly defective mutant, Cp149-Y132A, to examine the limits of the efficacy of assembly inhibitors.
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