HBV Mutation Detail Information

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Mutation Information
Mutation Site Y132A
Mutation Type Amino acid level
Gene/Protein/Region Type C
Literature Information
PubMed PMID 19196007
Published Year 2009
Journal Biochemistry
Title A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly.
Author Bourne CR,Katen SP,Fulz MR,Packianathan C,Zlotnick A
Evidence Here we use Cp149, the assembly domain of the hepatitis B virus capsid protein, together with an assembly defective mutant, Cp149-Y132A, to examine the limits of the efficacy of assembly inhibitors.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation