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Mutation Information
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Mutation Site
|
Y132A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
C |
Literature Information
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PubMed PMID
|
32702076
|
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Published Year
|
2020 |
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Journal
|
PLoS pathogens |
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Title
|
Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids. |
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Author
|
Hu Z,Ban H,Zheng H,Liu M,Chang J,Guo JT |
|
Evidence
|
As anticipated, except for Y132A mutant Cp that is deficient in capsid assembly, expression of all other Cp proteins resulted in the assembly of capsids in the cells (Fig 8A, particle gel assay).
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HBV Mutation Detail Information